Positive correlation between retinol binding protein 4 (RBP4) and triglyceride level in central obesity
نویسندگان
چکیده
منابع مشابه
Retinol-binding protein 4 in human obesity.
Studies in mice suggest that adipocytes serve as glucose sensors and regulate systemic glucose metabolism through release of serum retinol-binding protein 4 (RBP4). This model has not been validated in humans. RBP4 was highly expressed in isolated mature human adipocytes and secreted by differentiating human adipocytes. In contrast to the animal data, RBP4 mRNA was downregulated in subcutaneous...
متن کاملMacrophages are novel sites of expression and regulation of retinol binding protein-4 (RBP4).
Obesity is linked to a low-level chronic inflammatory state that may contribute to the development of associated metabolic complications. Retinol-binding protein 4 (RBP4) is an adipokine associated with parameters of obesity including insulin resistance indices, body mass index, waist circumference, lipid profile, and recently, with circulating inflammatory factors. Due to the infiltration of a...
متن کاملassociation of plasma retinol binding protein-4 (rbp4) and sonographic grading of fatty liver in obese iranian children
results rbp4 levels in obese children (19 482.9 ± 3 302.2 pg/ml) were higher than those found in the lean control group (14 295.68 ± 2 381.3 pg/ml) (p < 0.05). in the obese patients, rbp4 levels showed a significant correlation with the grade of fatty liver and bmi (p < 0.05). conclusions it was found that the level of rbp4 had a strong correlation with the severity of fatty liver. therefore, r...
متن کاملLiver retinol transporter and receptor for serum retinol-binding protein (RBP4).
Vitamin A (retinol) is absorbed in the small intestine, stored in liver, and secreted into circulation bound to serum retinol-binding protein (RBP4). Circulating retinol may be taken up by extrahepatic tissues or recycled back to liver multiple times before it is finally metabolized or degraded. Liver exhibits high affinity binding sites for RBP4, but specific receptors have not been identified...
متن کاملElevated Serum Triglyceride and Retinol-Binding Protein 4 Levels Associated with Fructose-Sweetened Beverages in Adolescents
BACKGROUND The metabolic effect of fructose in sugar-sweetened beverages (SSB) has been linked to de novo lipogenesis and uric acid (UA) production. OBJECTIVES This study investigated the biological effects of SSB consumption on serum lipid profiles and retinol-binding protein 4 (RBP4) among Taiwanese adolescents. METHODS We evaluated the anthropometric parameters and biochemical outcomes o...
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ژورنال
عنوان ژورنال: IOP Conference Series: Earth and Environmental Science
سال: 2018
ISSN: 1755-1307,1755-1315
DOI: 10.1088/1755-1315/125/1/012167